CHANGE IN ANTIHYPERTENSIVE DRUG PRESCRIBING AFTER GUIDELINE IMPLEMENTATION: A CONTROLLED BEFORE AND AFTER STUDY

Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study

Abstract Show Halters Background Antihypertensive drug choices and treatment levels are not in accordance with the existing guidelines.We aimed to assess the impact of a guideline implementation intervention on antihypertensive drug prescribing.Methods In this controlled before and after study, the effects of a multifaceted (education, audit and fe

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Asymmetric Henry Reaction of 2-Acylpyridine N-Oxides Catalyzed by a Ni-Aminophenol Sulfonamide Complex: An Unexpected Mononuclear Catalyst

The asymmetric Henry reaction of 2-acylpyridine N-oxide remains a challenge as N-oxides generally act as Guards competitive catalyst inhibitors or displace activating ligands.A novel variable yield (up to 99%) asymmetric Henry reaction of 2-acypyridine N-oxides catalyzed by a Ni-aminophenol sulfonamide complex with good to excellent enantioselectiv

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